{"id":543,"date":"2015-10-01T16:13:19","date_gmt":"2015-10-01T23:13:19","guid":{"rendered":"http:\/\/dentox.com\/botox-edu-news\/?p=543"},"modified":"2015-09-01T16:32:26","modified_gmt":"2015-09-01T23:32:26","slug":"botox-and-how-it-works","status":"publish","type":"post","link":"https:\/\/dentox.com\/botox-edu-news\/botox-and-how-it-works\/","title":{"rendered":"Botox and How it Works"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft size-medium wp-image-479\" src=\"https:\/\/dentox.com\/botox-edu-news\/wp-content\/uploads\/2015\/03\/Depositphotos_9017655_xs-200x300.jpg\" alt=\"doctor botox\" width=\"200\" height=\"300\" srcset=\"https:\/\/dentox.com\/botox-edu-news\/wp-content\/uploads\/2015\/03\/Depositphotos_9017655_xs-200x300.jpg 200w, https:\/\/dentox.com\/botox-edu-news\/wp-content\/uploads\/2015\/03\/Depositphotos_9017655_xs.jpg 283w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><span style=\"font-weight: 400;\">Botulinum toxin, more commonly known as Botox, is a neurotoxin created by the Clostridium botulinum bacteria. \u00a0Botox is used to treat some types of muscle-related conditions and to remove wrinkles by temporarily paralyzing the tiny muscles in the face. \u00a0While Botox is the most well-known form of botulinum toxin type A, it is also available under the names Dysport and Bocouture. \u00a0A second type of botulinum toxin, type B, is available under the name Myobloc.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Some important points about Botox<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Botox is used more than 6 million times every year in cosmetic procedures, making it the most popular cosmetic treatment. \u00a0It works by paralyzing the small muscles responsible for formation of wrinkles.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Botox can also be used to treat migraines, excessive sweating, some muscle-related \u00a0disorders, and some bladder and bowel conditions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The bacteria that produces botulinum toxin is found in the environment, especially the soil. \u00a0Environmentally, it is largely inactive. \u00a0However, it can cause botulism, a potentially fatal infection that causes respiratory failure. \u00a0A single gram can kill more than a million people, while two kilograms would be sufficient to kill the entire human population.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">History of Botox<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The bacteria that produces botulinum toxin is found in an inactive state in the soil and in sediment of untreated bodies of water. \u00a0It also lives in the intestinal tracts of many mammals, in the gills of fish, and in the organs of many shellfish. \u00a0The bacteria and its spores are generally harmless. \u00a0They only become a problem when the bacteria cells begin producing the toxin, usually when cell populations increase to a certain point.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Neurotoxins are so named because they target the nervous system and disrupt communication between the neurons. \u00a0botulinum toxin is divided into eight different types. \u00a0Of those, subtypes A, B, E, and occasionally F are the types that cause botulism in humans, while the others illness in other animals.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Botulinum toxin is thought to be among the most highly poisonous substances known. \u00a0It has been estimated that one gram could be lethal to approximately a million people. \u00a0Untreated, botulism can cause respiratory failure and can be fatal.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Botulinum toxin is a classic example of the idea that it is the dose that makes a substance poisonous. \u00a0Botulinum toxin has been used to treat a variety of muscle-related conditions, including cerebral palsy, as well as migraines and certain bladder and bowel conditions. \u00a0However, the most popular use of the toxin is to paralyze the small muscles under the skin of the face to minimize wrinkles. \u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Clinical use of botulinum toxin is based on the ability of the toxin to block nerve signals from reaching the targeted muscles so they are unable to contract.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Muscle contraction is caused when nearby nerves release the neurotransmitter acetylcholine. \u00a0The acetylcholine binds to receptors on the cells of the muscle, telling it to shorten. \u00a0Botulinum toxin prevents the neurons from releasing acetylcholine.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Uses of botulinum toxin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most people know of Botox as a cosmetic procedure for reducing wrinkles, especially around the eyes, but Botox has been approved for many other uses, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Eyelid spasms,<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Muscle spasms in the neck or shoulder, especially when the cause is unclear, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Migraines, especially those linked to craniofacial nerve compression,<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Excessive sweating, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Leaky bladder, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Crossed eyes, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Spastic limbs after a stroke<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Some cases of urinary incontinence, and<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Overactive bladder.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Aside from these FDA approved uses, botulinum toxin has also been used off-label for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Difficulty swallowing due to Achalasia (a problem with the esophagus, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Anal fissures and dysfunction, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Excessive salivation, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Nasal allergies, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Dysfunction of the Sphincter of Oddi (a band of muscle that controls flow of juices from the liver and pancreas into the intestines)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Muscle spasticity associated with cerebral palsy, and<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Uncontrolled spasms in the jaw, face, tongue, or vocal cords.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Botulinum toxin powder is given in minute doses. \u00a0A powder is diluted in saline and injected directly into the target muscles. \u00a0In most cases, the toxin begins to work in 24-72 hours, though in rare cases it can take up to 5 days before the full effects are noticed. \u00a0Botulinum toxin is not recommended for use in women who are pregnant or breastfeeding, or by anyone who has previously experienced an allergic reaction to botulinum toxin. <\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Safety and side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Treatment with botulinum toxin is usually well-tolerated by most people with few side effects. \u00a0In rare cases (about 1%), patients develop antibodies that make further treatments ineffective. \u00a0Some patients may experience additional side effects after treatment, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Discomfort, swelling, redness, or fluid retention near the injection site, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Numbness, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">General feeling of illness, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Nausea, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Temporary weakness or paralysis of muscles beyond the treated area, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Temporary drooping of the upper eyelids, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Temporary weakness of the lower eyelid or muscles controlling eye movement, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Difficulty swallowing, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Weakness in the neck,<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Flu-like symptoms, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Damage to the nerves in the neck, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Dysfunction of the gall bladder, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Double or blurred vision, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Bleeding, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Vision problems, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Dry mouth, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Rash or hives, <\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Fatigue, or<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Wheezing.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">New research is being conducted and new uses for Botox are being discovered all the time. \u00a0Following are some recent developments on Botox.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Botulinum toxin offers some relief to migraine sufferers, but does not seem to be quite the miracle cure that some believe, according to researchers from the Medical College in Milwaukee, WI in a study published in the (JAMA) Journal of the American Medical Association. \u00a0The researchers noted that Botox was not significantly more effective than a placebo.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Researchers in Australia have discovered a new way to block the toxin\u2019s action, which could lead to the development of new treatments for botulism. \u00a0The study is published in the International Journal of Biological Chemistry, August online edition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The journal JAMA Facial Plastic Surgery recently published a study that found Botox may effectively improve skin elasticity for as long as 4 months.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Botulinum toxin has been steadily increasing in popularity as a minimally invasive cosmetic procedure. \u00a0Since 2000, procedures have increased 700%. \u00a0In 2013, Botox was administered 6.3 million times for cosmetic procedures alone.<\/span><\/p>\n<p><b><a href=\"https:\/\/dentox.com\/all-courses\/botox-training\/\">Read about our Botox Training Course<\/a>.<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Botulinum toxin, more commonly known as Botox, is a neurotoxin created by the Clostridium botulinum bacteria. \u00a0Botox is used to treat some types of muscle-related conditions and to remove wrinkles by temporarily paralyzing the tiny muscles in the face. \u00a0While Botox is the most well-known form of botulinum toxin type A, it is also available [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1],"tags":[],"class_list":["post-543","post","type-post","status-publish","format-standard","hentry","category-botulinum-toxin"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Botulinum toxin, more commonly known as Botox, is a neurotoxin created by the 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